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Influenza A(H1N2) - Part 3

11 April 2002 - England.
Outbreak of influenza in a religious community [No longer available.] "An outbreak of influenza A has been reported from a religious community in the south of England. Approximately 120 individuals of all ages, both male and female, have been affected so far in the outbreak from a population of 350. All individuals in the community are reported to have received influenza vaccination in autumn 2001. The date for the majority of cases was between 9 and 20 March 2002, although sporadic cases continue to be reported. Cases have generally presented with 'flu-like illness consisting of fever, cough, headache and malaise. No cases have needed hospital admission. Approximately 20 individuals have been treated therapeutically with zanamivir in line with current Government recommendations.

Investigations have been carried out by the local communicable disease control team and microbiology laboratories. Specimens have been submitted to the National Influenza Laboratory at the Enteric, Respiratory, and Neurological Virus Laboratory (ERNVL): influenza A subtype H3N2 has been confirmed in 16 out of 18 cases from which specimens have been examined. Further investigation of the outbreak is currently underway." Source: CDR Weekly - PHLS.

11 April 2002 - Europe.
"No new cases of influenza A(H1N2) were reported to EISS in week 14/2002." Source: EISS Weekly Electronic Bulletin - Week 14, 2002.

13 April 2002 - United States -Virginia.
Contagious Illness at College Diagnosed. - [No longer available.] - Severe and highly contagious stomach flu, racks 120 students at women's college in Lynchburg., VA. Symptoms: vomiting, diarrhea, severe abdominal cramps and dehydration. Origin unknown. Source: Washington Post - Was: A4164-2002April12 (See the 9 January 2002 - China entry.)

[Note: These symptoms appear to be identical to those experienced by several people, adults and children, in the Columbus Mississippi area in April 2001. Those symptoms were coincident with the passing through of a dust storm from China.
See Global Developments: Spring Summer 2001 and The Pacific Dust Express.]

Another trans-Pacific dust storm was bearing down on the U.S. west coast about two weeks prior to the Lynchburg stomach flu outbreak. (See the 28 -30 March entries above.)

18 April 2002 - United States - Minnesota.
St. Cloud: Flu Outbreak Strikes Junior High - [No longer available.] Late-season outbreak "of the more serious Influenza B" leads to high absenteeism. Source: Yahoo! News - Was: http://dailynews.yahoo.com/h/4000/20020418/lo/1166755_1.html

24 April 2002 - Worldwide
Influenza B viruses currently circulating worldwide can be divided into two antigenically distinct lineages: B/Yamagata/16/88 and B/Victoria/2/87. B/Yamagata viruses have circulated widely since 1990, and the B component of the current influenza vaccine belongs to this lineage. Since 1991, B/Victoria viruses have not been identified outside of Asia. However, since March 2001, B/Victoria lineage viruses have been identified in many countries, including the United States. Of the 96 U.S. influenza B viruses characterized antigenically this season, 53 were of the B/Yamagata lineage, and 43 were of the B/Victoria lineage. Source:CDC MMWR 2002;51:276-279 (Reprinted in the Journal of the American Medical Association
JAMA April 24, 2002 -- Volume 287, No. 16, page 2068. - [No longer available.]
Was: http://jama.ama-assn.org/issues/v287n16/fpdf/jwr0424.pdf

24 April 2002 - United States - Alaska.
Flu-like symptoms hit Anchorage schools - [No longer available.]. A recent high rate of school absenteeism has lead to the speculation that flu might be mounting a late season attack on Anchorage. No flu confirmation yet by state epidemiologists. Source: MSNBC, Anchorage, AK. - Google news search.
Was: http://www.msnbc.com/local/ktuu/m175530.asp

25 April 2002 - Greece.
Greece Reports New Cases of Possible Killer Bug - [No longer available.] - A mystery virus has been blamed for several deaths. Schools in Athens shut down temporarily. Doctors are still trying to identify the strain of virus, which is thought to belong to the enterovirus group. Source: Reuters.com - Health News Coverage. (JAVA intensive site!)
Was: http://www.reuters.com/news_article.jhtml?type=healthnews&storyID=882321

- - -

The following two paragraphs and histograms were placed in this file on 26 April 2002 and modified on 29 April 2002.

It has widely been stated that the new A(H1N2) virus subtype appears to have arisen by reassortment of the two human viruses A(H1N1) and A(H3N2). With that possibility in mind, the following (edited to fit your printer and to equalize vertical scales for both seasons) histograms from the United States CDC are provided. The graphs show that during the 2000-2001 flu season there was a substantial amount of A(H1N1) isolates found but extremely little A(H3N2). In 2001-2002 the situation was reversed -- very little A(H1N1) but a lot of A(H3N2).

Comparison of flu seasons

Three questions arise. Where and when were there sufficient quantities of the two subtypes intermingling, in order for the reassortment process to take place? Were there multiple reassortment sites around the globe? Is there any evidence of migration from the various points of origin of the new subtype? (These may be the wrong questions.)

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2 May 2002 - Wisconsin USA
Influenza A(H1N2) Viruses in Wisconsin - [No longer available.] - The initial Wisconsin isolate was recovered from a specimen collected December 7, 2001 from a six month old child [in Outagamie county]. Eight additional A(H1N2) isolates were detected between January 11 and February 11, 2002 from patients aged 9 through 31 years. Seven of these came from St. Vincent Hospital in Greenbay [Brown county]. All of the Wisconsin H1N2 isolates to date have been from [the] two adjacent counties. Source: Wisconsin State Laboratory of Hygiene, Madison, WI. [Names of counties added.]
Was: http://www.virology.org/Newsletter/May02/May0205.html


H1N2 Counties
in Wisconsin

The Wisconsin counties where H1N2 viruses were isolated (Outagamie and Brown) were never listed as active on FluWatch.com during the 2001-2002 flu season. The locations of the counties that were listed as such are shown as green dots.

The following diagram shows a comparison of reported activity for the 2000-2001 and 2001-2002 flu seasons. It is derived mainly from the FluWatch.com '01-'02 Trend Map and from FluWatch.com daily reports. Activity levels shown in slightly darker colors are based on archived data furnished by the National Flu Surveillance Network™ (NFSN).

The lighter grey background area corresponds to the October 1 - March 31 time frame of the FluWatch Trend Map. (Levels for Rhode Island and the District of Columbia are omitted in the parts derived from the Trend Map because their images there are too small to be used unambiguously.)

The purpose for showing the seasonal patterns here, is to look for unusual influenza activity, i.e., unexpected bumps or valleys, especially in the first month or two following the March 30, 2001 Venus inferior conjunction with its accompanying solar storm. See the introductory section of Global Developments: Spring-Summer 2001. [Inserted on 9 July 2002. Latest update was on 25 July 2002.]

One bump of interest on the above graph starts toward the end of March 2002 and tapers off in early April. (See the orange colored alert activity.) Coincident with the bump was a diluted dust storm which was moving across the U.S. from West to East. It had originated in Asia. (See the entries for 20 -30 March above.) Now, there may be no connection between the arrival of the Asian dust and a few odd late season influenza-like outbreaks (false cause is easy), but on the other hand the beginning of The First Wave of the 1918 influenza Pandemic, at least at Fort Riley in Kansas, was accompanied by a significant dust storm.

What might have been a pre-season influenza herald event in the United States took place in July through September of 2001. (See the first graph in the section USA Influenza 2001-2002 - Part 2.)

That nationwide flurry of summer activity (in 2001) may have been related to other late season global influenza-like activity. See the 14 April 2001 (Pakistan) and 23 May 2001 (Indonesia) entries on the Global Developments: Spring - Summer 2001- Part I page. [Added 29 June 2002. Re-worked on 9 July 2002]

29 May 2002 - Canada - Alberta
For chronological stats on A(H1N2) in Alberta, Canada, see Alberta's Viral Watch.

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